Custom Peptides
Cayman Chemical 20 S-ProtopnaxadIol 10mg
A sapogenin; cytotoxic to MT-4 human T cell leukemia cells (CC50 = 7.2 µM); inhibits the growth of human A549 human lung carcinoma, SKOV3 ovarian adenocarcinoma, SK-MEL-2 melanoma, and K562 chronic leukemia cells (EC50s = 9.8-20 µM), as well as P388 and L1210 murine leukemia cells (EC50s = 9.8 and 10, respectively); inhibits the growth of H. pylori in vitro (MIC = 50 UG/ml)
Cayman Chemical IsorhoIfolIn 10mg
A flavonoid glycoside with diverse biological activities; inhibits MMP-1, MMP-3, and MMP-13 (IC50s = 0.33, 2.45, and 0.22 µM, respectively); has antimutagenic properties in the E. coli WP2 tryptophan reverse mutation assay at 2 µM; active against S. aureus and P. aeruginosa in agar diffusion assays at 140 UG/ml
Cayman Chemical 4acetoxy METhydrochLRIde 10mg
An analytical reference standard categorized as a tryptamine; induces the HTR in mice; intended for research and forensic applications
Cayman Chemical EnoxacIn-d8hydrochlorIde 10mg
An internal standard for the quantification of enoxacin by GC- or LC-MS
Cayman Chemical 11-DehydrocortIcosteron 10mg
An endogenous mineralocorticoid; increases Na+/K+-ATPase mRNA expression in vascular smooth muscle cells and inhibits aldosterone action in B. marinus toad bladder tissue in a concentration-dependent manner; decreases the sodium/creatine ratio and increases the potassium/creatine ratio in rat urine in a dose-dependent manner in a model of carbenoxolone-induced 11β-hydroxysteroid dehydrogenase inhibition; chronic administration increases plasma glucocorticoids levels, body weight gain, and adiposity, as well as induces insulin resistance in mice
Cayman Chemical 2-methoxy Estron 10mg
An active metabolite of estrone; inhibits proliferation of isolated bovine brain-derived capillary endothelial cells (IC50 = 11.5 µM); increases levels of 6-keto PGF1α in HUVECs at 0.001, 0.01, and 0.1 µM; reduces ovariectomy-induced increases in serum cholesterol in rats at 0.5 mg/kg
Cayman Chemical BetulnIc ACD propargyl St 10mg
An alkyne derivative of betulinic acid; has been used in click chemistry reactions for the synthesis of cytotoxic anticancer betulinic acid derivatives
Cayman Chemical HypocrelIn B 10mg
A fungal metabolite; decreases the viability of, and induces apoptosis in, MDA-MB-231 breast cancer cells when used in the presence of ultrasound exposure; increases the production of ROS in MDA-MB-231 cells at 2.5 µM with concomitant ultrasound exposure; active against MRSA at 20 µM in combination with ultrasound sonication
Cayman Chemical 4-EAPBhydrochlorIde 10mg
An analytical reference standard categorized as a benzofuran; intended for research and forensic applications
Cayman Chemical JWH 073 4mthylnphthyl nl 10mg
Differs structurally from JWH 073 by having a methyl group added at the 4 position of the naphthyl rings; a similar addition to JWH 018 results in an analog which has higher affinities for both cannabinoid receptors
Cayman Chemical 4-methyl ErlotInIb 10mg
A methylated derivative of erlotinib; has been used as an internal standard for the quantification of erlotinib and erlotinib metabolites in human plasma
Cayman Chemical SGernylgernylLglutathIon 10mg
A P2RY8 ligand; selectively induces internalization of P2RY8 over S1P2, GPR55, CysLT1 receptor, and CysLT2 receptor at 100 nM; inhibits CXCL12-induced migration of P2RY8-expressing WEHI-231 B cell lymphoma cells and isolated human tonsil germinal center B cells at 10 nM
Cayman Chemical 2-EthylamIno-1-phenylbutn 10mg
An analog of N-ethylamphetamine that is characterized by an ethyl group replacing methyl at the α position