Custom Peptides
Cayman Chemical 1 2DIoleoyl3Lauroylracgl 10mg
A triacylglycerol; has been found in date seed oil and the fat body of male B. lapidarius bumblebees
Cayman Chemical 1MyrIstoyl2LInoleoyl3Pal 10mg
A triacylglycerol; has been found in palm and vegetable oils
Cayman Chemical ProcaterolhydrochlorIde 10mg
An adrenergic receptor agonist; selective for β2-ARs over β1-ARs (Kds = 46 and 4,000 pM, respectively); binds more potently to β2-ARs in isolated guinea pig lung than to β1-ARs in isolated guinea pig cardiac ventricle in the presence (IC50s = 175 and 1,660 nM, respectively) and absence of GTP (IC50s = 55.1 and 1,660 nM, respectively); inhibits acetylcholine-induced contractions in isolated guinea pig trachea (EC50 = 10.5 nM); inhibits histamine-induced airflow obstruction in a guinea pig model of ovalbumin-sensitized asthma at 10 μg/ml via inhalation
Cayman Chemical 17-hydroxy WortmnIn 10mg
An analog of wortmannin; irreversibly binds PI3K; inhibits recombinant PI3K and mTOR (IC50 = 2.7 and 193 nM, respectively) and prevents the growth of LNCap cells (IC50 = 1.46 μM)
Cayman Chemical BIcyclo ProstaglndIn E1 10mg
Bicyclo Prostaglandin E1 (bicyclo PGE1) is a stable, base-catalyzed transformation product of the PGE1 metabolite 13,14-dihydro-15-keto PGE1. Bicyclo PGE1 is a stable, base-catalyzed transformation product of the PGE1 metabolite 13,14-dihydro-15-keto PGE1. 13,14-dihydro-15-keto PGE1 itself is a metabolite of PGE1{182,2126} found in human plasma at a median level of 10 pg/ml.{4383} Due to the inherent instability of 13,14-dihydro-15-keto PGE1, it is advisable to quantify it as bicyclo PGE1 to estimate PGE1 biosynthesis or metabolism in vivo.
Cayman Chemical HexahydrocurcumIn 10mg
A natural product and an active metabolite of curcumin; has anti-inflammatory, antioxidant, and anticancer properties; reduces PMA-induced PGE2 production by 37% in human colonic epithelial cells (20 µM); inhibits LPS-induced overproduction of nitric oxide in RAW 264.7 macrophage cells (3.125-25 µM); inhibits LPS-induced iNOS and COX-2 upregulation and NF-κB activation (50 µM); prevents formation of aberrant crypt foci in a dimethylhydrazine rat model of colon cancer
Cayman Chemical NpentadecnoylLHomoserIn 10mg
A bacterial quorum-sensing signaling molecule; activates the LasR quorum sensing receptor of bacteria in a reporter assay; induces GFP production in a P. putida F117 reporter strain expressing the pKR-C12 quorum-sensing operon at 0.094 nM
Cayman Chemical CardIogenol ChydrochLRIde 10mg
Induces the differentiation of MHC-positive cardiomyocytes from embryonic stem cells with an EC50 value of 0.1 µM
Cayman Chemical Mangostn 10mg
A xanthone with diverse biological activities; inhibits growth of MRSA and MSSA (MICs = 6.25-12.5 and 6.25-25 μg/ml, respectively), P. falciparum (IC50 = 3 μg/ml), and M. tuberculosis (MIC = 6.25 μg/ml); inhibits FASN (IC50 = 24.83 μM); induces cell cycle arrest at the G2/M phase and intrinsic and mitochondrial apoptosis in MCF-7 breast cancer cells; inhibits LPS-induced nitric oxide and PGE2 production in RAW264.7 cells; reduces neutrophil infiltration and TNF-α and IL-1β production in a mouse model of carrageenan-induced peritonitis
Cayman Chemical NBenzylacetamIdInhydrobro 10mg
A potent inhibitor of iNOS (IC50 = 0.20 μM), with over 1,000-fold selectivity compared to eNOS (IC50 = 350 μM)
Cayman Chemical 6-hydroxy MetndIenon 10mg
An analytical reference standard categorized an anabolic androgenic steroid metabolite of metandienone; intended for research and forensic applications
Cayman Chemical SphngosInd14 1 10mg
A bioactive sphingolipid; has been found in B. mori, P. clarkii, and A. aurita extracts; increases the germination rate of N. rileyi (EC50 = 0.0102 ng/ml); inhibits PKC in vitro (IC50 = 7.3 mol %); inhibits PMA-induced superoxide generation in neutrophils and reduces growth of CHO cells (IC50s = 19 and 8 μM, respectively)
Cayman Chemical TetrabenazIn 10mg
An inhibitor of VMAT2 that is selective over VMAT1 (Kis = 97 and >20,000 nM, respectively, in a serotonin uptake assay); dose-dependently reduces levels of the monoamines norepinephrine, dopamine, and 5-HT in rat brain; has been used to induce depressive-like behavior in animal models; improves performance in balance beam and rotarod tests and prevents decreases in the number of striatal MSNs in a YAC128 transgenic mouse model of Huntington’s disease at 5 mg/kg
Cayman Chemical Tafluprost ethyl ester 10mg
A form of tafluprost which may have increased lipid solubility compared to the free acid
Cayman Chemical 1R 3S3AmInocyclopentnol 10mg
A synthetic intermediate useful for pharmaceutical synthesis.